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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 115 unique cruise itineraries from 8 leading cruise lines. March is the most popular month to join a luxury cruise around South America with 239 departures starting between June 2024 and March 2026.
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115 Cruises (239 Cruise Departures)
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
INSIDE
$5,330
OCEANVIEW
$6,365
BALCONY
$7,515
SUITE
$8,780
From 5,330
View Trip
11 Day Peru & Chile Voyage with Azamara Cruises
Cruise
 (1)

11 Days (10 Nights) Lima to San Antonio
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 23 January 2025
Countries Visited: Peru, Chile
Circle Club Voyage
INSIDE
$4,689
OCEANVIEW
$5,408
BALCONY
$6,271
SUITE
$9,720
From 4,689
View Trip
10 Day Ocean Voyage: Hanga Roa - Ushuaia with Ponant
Cruise
 (1)

10 Days (9 Nights) Hanga Roa to Ushuaia
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 November 2024
Countries Visited: Easter Island, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$3,296
BALCONY
$3,551
SUITE
$5,315
Save 54
From 3,296
View Trip
26 Day Carnival Rio & Amazon Voyage with Azamara Cruises
Cruise
 (1)

26 Days (25 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 February 2025
Countries Visited: Argentina, Uruguay, Brazil, French Guiana (+1 more), Barbados
Circle Club Voyage
INSIDE
$9,243
OCEANVIEW
$11,052
BALCONY
-
SUITE
-
From 9,243
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$18,569
SUITE
$28,614
Save 327
From 17,393
View Trip
11 Day Brazilian Brilliance with Oceania Cruises
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$5,124
OCEANVIEW
$5,807
BALCONY
$6,421
SUITE
$8,955
Save 2,036
From 5,124
View Trip
15 Day Wild Guianas To The Amazon Basin with Seabourn
Cruise

15 Days (14 Nights) Bridgetown to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$18,357
SUITE
$34,851
From 18,357
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,197
SUITE
$29,334
From 15,197
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2024 to Jul 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$21,681
SUITE
$64,944
Save 656
From 21,681
View Trip
12 Day Crossing the Equator: Barbados to Brazil with Scenic
Cruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 November 2024
Countries Visited: Brazil, French Guiana, Barbados
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,960
SUITE
$10,207
Save 10,570
From 6,960
View Trip
22 Day The Complete Amazon Experience & Coast Of Brazil with Seabourn
Cruise

22 Days (21 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,065
SUITE
$41,821
From 24,065
View Trip
12 Day Wonders of the Galápagos & Machu Picchu with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Aug 2024 to Nov 2024
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
Exclusive Solo Offer
From 26,490
View Trip
31 Day South America Connoisseur with Oceania Cruises
Cruise

31 Days (30 Nights) San Antonio to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,732
SUITE
$23,424
Save 2,128
From 16,732
View Trip
23 Day Beauty At The End Of The World with Regent Seven Seas
Cruise

23 Days (22 Nights) Rio de Janeiro to Santiago
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 25 January 2025
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,501
SUITE
$16,980
Save 17,549
From 15,501
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Guayaquil to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Oct 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$30,987
SUITE
$47,421
From 30,987
View Trip
21 Day Lima to Buenos Aires with Silversea
Cruise

21 Days (20 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Argentina, Chile, Peru
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$25,344
From 25,344
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$22,473
BALCONY
$25,641
SUITE
$38,709
From 22,473
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Aug 2025
Countries Visited: Ecuador, Galapagos
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$13,414
SUITE
$19,206
Save 235
From 13,414
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Northern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Feb 2025 to Nov 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 26,465
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 16 March 2026
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$10,692
BALCONY
$12,771
SUITE
$28,611
From 10,692
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departure: 21 March 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$37,323
From 20,592
View Trip
13 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 22 March 2025
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,449
SUITE
$18,706
Save 5,646
From 14,449
View Trip
13 Day Bounty Of Brazil with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 January 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$6,185
OCEANVIEW
$6,947
BALCONY
$7,709
SUITE
$10,719
Save 2,045
From 6,185
View Trip
13 Day Valparaiso to Puerto Williams with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 07 November 2024
Countries Visited: Argentina, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,593
BALCONY
$14,949
SUITE
$19,800
From 10,593
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departures: Nov 2024 to Oct 2025
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,623
SUITE
$14,365
Save 7,607
From 10,623
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$9,405
BALCONY
$11,385
SUITE
-
From 9,405
View Trip
13 Day Tango & Samba Celebration with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 14 January 2025
Countries Visited: Argentina, Uruguay, Brazil
Cabin Upgrade Offer
INSIDE
$6,283
OCEANVIEW
$6,897
BALCONY
$6,897
SUITE
$10,214
From 6,283
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 12 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,197
SUITE
$29,334
From 15,197
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,672
From 7,672
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,334
From 17,919
View Trip
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